Sickle cell disease is a group of inherited blood disorders that center on red blood cells which can function abnormally resulting in small blood clots, chronic anemia, painful events, and potential complications associated with tissue and organ damage. These blood disorders include sickle cell anemia, Mediterranean blood disease, the sickle beta thalassemia syndromes, and hemoglobinopathies in which the sickle cell hemoglobin is in association with other abnormal hemoglobin in sufficient concentration to cause the red blood cell to sickle.
Treatments for sickle cell anemia are primarily focused on relieving the pain and complications caused by the symptoms associated with this disease as the only potential cure for sickle cell is a bone marrow transplant which has high risk factors which can be fatal and finding a donor with an exact match is extremely difficult.
Persons of African descent are most likely to have sickle-cell anemia, but it is also relatively common among people of Mediterranean, Arab, and South Asian ancestry, and it is not unknown among Caucasians. Inheriting a gene for sickle-cell anemia from both parents results in full expression of the disease. Inheriting a gene for sickle-cell anemia from only one parent causes changes in hemoglobin that are identifiable by blood tests, but does not cause symptoms.
Sickle Cell Anemia is caused when the oxygen-carrying protein, hemoglobin, is shaped irregularly in a person's blood cells. This irregular shape can cause the cells difficulty passing through some veins and makes them extremely fragile. The delicate nature and easy breaking of these cells through smaller blood vessels can result in the need for a constant recreation of the cells. Although this disease is hereditary, not all carriers of the gene will develop sickle cells.
The heart must work harder to pump anemic blood, causing a rapid heart rate, fatigue, weakness, dizziness, and other complications. Hypoxia can lead not only to a risk of heart failure, but to more sickling of the blood because of further oxygen shortages.
Many will suffer from vision loss and the retina of one or both eyes may become damaged. It is a known fact that since the immunity is suppressed that the sufferer may suffer from serious infections. Blockages in the blood vessels, trouble with the lungs, and damage to the organs and the bones in the body may also be occur.Since this condition is a genetically inherited disorder, it may not be currently possible to completely cure this disease. However, a majority of the symptoms can be prevented or reduced with a judicious combination of Ayurvedic medicines. It should be remembered that all patients suffering from this condition should be under the regular supervision and treatment of a Hematologist.
Sickle cells have a shorter life span than normal red blood cells. This results in chronic anemia and reduced oxygen to the tissues of the body. In addition, sickle cells are less flexible than normal red blood cells. This presents a problem since they can become trapped in the small blood vessels preventing blood flow to the body's tissues. This compromise in the delivery of oxygen to the tissues results in pain and potential damage to the associated tissues and organs.
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